Press Releases

Elicio Therapeutics Presents Updated Preclinical Data at the 2021 Vaccines Summit Demonstrating that ELI-005, a Lymph Node Targeted Amphiphile Vaccine, Induces Potent Cellular and Humoral Immunity to SARS-CoV-2
Elicio Therapeutics, a clinical-stage biotechnology company developing a pipeline of novel immunotherapies for the treatment of cancer and other diseases, today announced positive preclinical data demonstrating that ELI-005, a protein subunit vaccine containing the lymph node-targeted Amphiphile-CpG adjuvant (AMP-CpG), induces potent cellular and humoral immunity to SARS-CoV-2 at the 2021 Vaccines Summit, being held virtually on September 20-22, 2021. » Read more
Elicio Therapeutics Announces Virtual Presentation of Data on its Amphiphile-CpG Adjuvant at the Vaccines Summit 2021
Elicio Therapeutics, a clinical-stage biotechnology company developing a pipeline of novel immunotherapies for the treatment of cancer and other diseases, today announced that it will present preclinical data on its AMP-CpG adjuvant (AMP-CpG) at the Vaccines Summit 2021, being held virtually from September 20-22, 2021 » Read more
Elicio Therapeutics Presents Preclinical Data on AMP TCR-T Combination Therapy in Solid Tumors at the CAR-TCR Annual Summit 2021
Elicio Therapeutics, a clinical-stage biotechnology company developing a pipeline of novel immunotherapies for the treatment of cancer and other diseases, today announced the initiation of AMPLIFY-201, a Phase 1/2 dose-escalation study evaluating the safety and preliminary efficacy of ELI-002, the Company’s therapeutic vaccine that is being investigated as a potential treatment for patients with KRAS-driven tumors who have minimal residual disease following surgical tumor resection. » Read more
Elicio Therapeutics Announces Initiation of Its Phase 1/2 Dose-Escalation Study of ELI-002 (AMPLIFY-201) in KRAS-Driven Cancers
Elicio Therapeutics, a clinical-stage biotechnology company developing a pipeline of novel immunotherapies for the treatment of cancer and other diseases, today announced the initiation of AMPLIFY-201, a Phase 1/2 dose-escalation study evaluating the safety and preliminary efficacy of ELI-002, the Company’s therapeutic vaccine that is being investigated as a potential treatment for patients with KRAS-driven tumors who have minimal residual disease following surgical tumor resection. » Read more
Elicio Therapeutics Announces FDA Clearance of IND application for ELI-002– A Therapeutic Vaccine Targeting mutated KRAS Cancers
CAMBRIDGE MA., February 23, 2021 – Elicio Therapeutics, a private biotechnology company developing a pipeline of potent immunotherapies based on its proprietary lymph-node targeting Amphiphile technology, announced it has received Investigational New Drug (IND) clearance from the U.S. Food and Drug Administration for ELI-002. ELI-002 is an Amphiphile (AMP) KRAS therapeutic vaccine containing AMP mKRAS peptides and a proprietary AMP CpG adjuvant, administered subcutaneously. » Read more
Elicio Therapeutics Secures a Total of $73 Million in Series B Financing
CAMBRIDGE MA., February 17, 2021 – Elicio Therapeutics, a private biotechnology company developing a pipeline of potent immunotherapies based on its proprietary lymph node targeting technology, announced the successful completion of Series B financing bringing the total funds raised in the current round to $73 million. Elicio funding has been established from an international investor base, including multiple strategic and institutional investors » Read more
Elicio Therapeutics to discuss success of Amphiphiles enabled T cell therapies at CAR-TCR Digital Summit Europe
CAMBRIDGE MA., FEBRUARY 15, 2021 (BusinessWire) – Elicio Therapeutics, a private biotechnology company developing a pipeline of potent immunotherapies based on its proprietary lymph node targeting technology, today announced Christopher Haqq, M.D., Ph.D., Elicio’s Executive Vice President, Head of Research and Development, and Chief Medical Officer, will co-lead a workshop, “Improving Efficacy and Solid Tumor Infiltration with Combination […] » Read more
Elicio Therapeutics’ SARS CoV-2 vaccine demonstrates T Cell responses >25 fold higher than benchmark vaccines Preclinical data published in Science Advances
A proprietary lymph node targeting adjuvant for COVID-19 has elicited high magnitude T cell responses alongside potent neutralizing antibody induction; the studies are published in the February 5 issue of Science Advances. Significantly, the magnitude of T cell responses substantially exceeded prior observations in mouse models with benchmark COVID-19 vaccines. ELI-005, Elicio Therapeutics’ novel SARS-CoV-2 vaccine, […] » Read more
Annette Matthies, PH.D., Joins Elicio Therapeutics as Chief Business Officer
Elicio Therapeutics, a private biotechnology company developing a pipeline of potent immunotherapies based on its proprietary lymph node targeting technology, announced today that Annette Matthies, Ph.D., has joined as Chief Business Officer. At Elicio, she will lead all business and corporate development efforts, including acquisitions, licensing agreements, partnerships, and portfolio management. » Read more
Elicio Announces Additions to Board of Directors
Elicio Therapeutics, a next generation immunotherapy company, has named Daphne Karydas, Chief Financial Officer at Syndax Pharmaceuticals and Carol Ashe, Chief Business Officer at the New York Genome Center, to its board of directors.   » Read more
Elicio Therapeutics Announces Poster Presentation at 2020 Society for Immunotherapy of Cancer Annual Meeting
Lymph node-targeted AMP-vaccine enables tumor-directed mKRAS-specific immune responses with potent polyfunctional and cytolytic activity. » Read more
Elicio Therapeutics VP of Research and Founding Scientist talk COVID19
We are thrilled to feature our VP of Research Pete DeMuth, and Elicio’s Founding Scientist Darrell Irvine, as a guest on Julian Adams, CEO of Gamida Cell, new podcast “Science Side by Side” where they discuss the development, approval and delivery of a vaccine to prevent #COVID19. » Read more
Elicio Therapeutics and Moffitt Collaborate to Study AMP-CD19 in Combination with CD19 CAR T cells
Elicio Therapeutics, a next generation immuno-oncology company, today announced that it has established a collaboration with the Moffitt Cancer Center to characterize combination therapies pairing Elicio’s CD19 Amphiphile and a universal FITC Amphiphile with CD19 CAR T cells. » Read more
Lymph node targeting COVID-19 vaccine induces up to 25-fold more T cells over benchmark vaccines and >265-fold greater antibody levels than recovering patients
Preclinical data from a lymph node targeted COVID-19 vaccine candidate showed potent CD8 and CD4 T Cells in lung tissue and respiratory fluid » Read more
Adrian Bot, MD, PhD, Named to Elicio Therapeutics Scientific Advisory Board
Elicio Therapeutics, a next generation immuno-oncology company, announced today that Adrian Bot, MD, PhD, Vice President of Translational Medicine at Kite, a Gilead Company, has joined Elicio’s Scientific Advisory Board. » Read more
Elicio Therapeutics and National Cancer Institute Collaborate to Study ELI-002 mutant KRAS Targeting Mechanism
Elicio Therapeutics, a next generation immuno-oncology company, today announced that it has established a collaboration with the National Cancer Institute (NCI) to characterize T cell responses to ELI-002 in animals. » Read more
Esther Welkowsky Joins Elicio Therapeutics as Vice President Clinical Operations
Esther Welkowsky, an accomplished clinical operations leader with over 15 years of biotechnology development experience across T cell immunotherapy, biologics, and small molecules, Will lead Elicio’s oversee clinical operations and assist in defining development strategy, guiding protocol design, study conduct, and regulatory compliance. » Read more
Elicio Therapeutics to discuss novel lymph node vaccine targeting seven key mKRAS mutations at RAS – Targeted Drug Discovery Summit in Vienna, Austria
Elicio Therapeutics, a next generation immuno-oncology company, today announced Peter DeMuth, PhD., Elicio Vice President of Research, will present “Targeting the Lymph Nodes to Enhance Mutant KRAS-Specific Vaccine Responses,” at the upcoming RAS-Targeted Drug Discovery Summit in Vienna, Austria, from February 25 to 27, 2020. » Read more
Elicio Therapeutics and Natera To Collaborate in Phase I/II Pancreatic Cancer Study of ELI-002
Elicio Therapeutics and Natera, Inc.(NASDAQ: NTRA) today announced their collaboration in a prospective, multicenter Phase 1/2 study of ELI-002, an Amphiphile immuno-oncology therapeutic targeting KRAS mutations in the adjuvant setting for patients with pancreatic ductal adenocarcinoma (PDAC) who have undergone neoadjuvant chemotherapy followed by pancreatectomy. IND submission for the 108-patient trial which will open at 10-12 US sites will be in the first half of 2020. » Read more
FIERCE BIOTECH: Chutes and Ladders
Cambridge, Massachusetts-based Elicio Therapeutics has hired Christopher Haqq, M.D., Ph.D., as CMO and executive vice president and head of R&D. Haqq was the first employee and CMO of Atara Biotherapeutics, and later its CSO. » Read more
Physician-Scientist Christopher Haqq M.D., Ph.D. Joins Elicio Therapeutics as Research and Development Head
Will lead Elicio’s transition to clinical-stage and oversee, prioritize and advance the company’s rich pipeline of immunotherapies. » Read more
Elicio Therapeutics Completes $33 Million Series B Financing
Proceeds will advance Elicio’s pipeline including an Amphiphile Vaccine targeting mKRAS-Driven Cancers. CAMBRIDGE MA., October 2nd, 2019 (BusinessWire) – Elicio Therapeutics, a next generation immuno-oncology company, announced today that it has closed its $33 million Series B financing. » Read more
Elicio Therapeutics Presents In Vivo Data for a Universal Amphiphile Vaccine Targeting KRAS-Driven Cancers
Demonstrates robust immune responses and cytolytic activity targeting the seven key mKRAS mutations CAMBRIDGE MA., AUGUST 7th, 2019 (BusinessWire) – Phase One patient data from a potential therapy targeting a single KRAS mutation, formerly considered “undruggable,” has been introduced in 2019. Now, Elicio Therapeutics, a next generation immuno-oncology company, is presenting significant preclinical data from a novel lymph-node […] » Read more
Elicio Therapeutics Co-founder, Darrell Irvine, Co-authors Research Published in Science Demonstrating Novel AMP-CAR-T Approach to Enhance CAR-T Function in Solid Tumor Cancers
Elicio Therapeutics today announced that studies of its Amphiphile platform in combination with CAR-T therapy (AMP-CAR-T) have shown that activation of CAR-T cells in the lymphatic system gives massive CAR-T cell expansion, and significant functional improvements including enhanced CAR-T cell infiltration of solid tumors, increased anti-tumor cytolytic potential, and improved cytokine response. » Read more
BioCentury: Elicio’s cancer vaccine boosts CAR Ts for solid tumors
Elicio Therapeutics (Cambridge, Mass.), which launched in March, exclusively licensed the platform, Amphiphile, from co-founder Darrell Irvine at the Koch Institute for Integrative Cancer Research at Massachusetts Institute of Technology. » Read more
Immuno-Oncology Company Elicio Therapeutics Launches with Novel Vaccine & Immunotherapy Platform to Treat an Array of Cancers
$30 Million Financing Backing MIT-Developed Amphiphile Platform to Target a Wide-Range of Immunogens to the Lymph Nodes, the “Brain Center’ of the Immune Response CAMBRIDGE MA., March 27, 2019 (BusinessWire) – Elicio Therapeutics, a next generation immuno-oncology company, engineering therapies for cancer killing immune responses, launched today and announced the appointment of Robert Connelly as […] » Read more